Recombinant Human SIGIRR
Cat.No. : | SIGIRR-1681H |
- Specification
- Gene Information
- Related Products
Cat. No. : | SIGIRR-1681H |
Description : | Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family. It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling. It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium. |
Molecular Weight : | The predicted molecular weight of Recombinant Human SIGIRR is Mr 39 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 55-60 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >90% by SDS Page and analyzed by silver stain. |
Endotoxin : | <0.1 ng per 1 µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain [ Homo sapiens ] |
Synonyms : | SIGIRR; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; TIR8; MGC110992; single Ig IL-1R-related molecule; single immunoglobulin domain IL1R1 related; Single immunoglobulin domain-containing IL1R-related protein; Toll/interleukin-1 receptor 8; single immunoglobulin and toll-interleukin 1 receptor domain; Single Ig IL-1-related receptor |
Gene ID : | 59307 |
mRNA Refseq : | NM_001135053 |
Protein Refseq : | NP_001128525 |
MIM : | 605478 |
UniProt ID : | Q6IA17 |
Chromosome Location : | 11p15.5 |
Function : | protein binding; transmembrane receptor activity |
Products Types
◆ Recombinant Protein | ||
SIGIRR-5059R | Recombinant Rat SIGIRR Protein, His (Fc)-Avi-tagged | +Inquiry |
Sigirr-5875M | Recombinant Mouse Sigirr Protein, Myc/DDK-tagged | +Inquiry |
SIGIRR-2054M | Recombinant Mouse SIGIRR Protein (1-117 aa), His-tagged | +Inquiry |
SIGIRR-4483H | Recombinant Human SIGIRR Protein, His (Fc)-Avi-tagged | +Inquiry |
Sigirr-10614M | Recombinant Mouse Sigirr Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SIGIRR-2773MCL | Recombinant Mouse SIGIRR cell lysate | +Inquiry |
SIGIRR-1091HCL | Recombinant Human SIGIRR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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