"OXCT1" Related Products


Recombinant Human OXCT1

Cat.No.: OXCT1-30531TH
Product Overview: Recombinant fragment of Human OXCT1 with a N terminal proprietary tag: predicted molecular weight 31.57 kDa.
Description: This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
Molecular Weight: 31.570kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the 3-oxoacid CoA-transferase family.
Gene Name: OXCT1 3-oxoacid CoA transferase 1 [ Homo sapiens ]
Official Symbol: OXCT1
Synonyms: OXCT1; 3-oxoacid CoA transferase 1; 3 oxoacid CoA transferase , OXCT; succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial; SCOT;
Gene ID: 5019
mRNA Refseq: NM_000436
Protein Refseq: NP_000427
MIM: 601424
Uniprot ID: P55809
Chromosome Location: 5p13
Pathway: Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Ketone body metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
Function: 3-oxoacid CoA-transferase activity; 3-oxoacid CoA-transferase activity; protein homodimerization activity; transferase activity;

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