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Recombinant Human PBK

Cat.No.: PBK-29677TH
Product Overview: Recombinant full length human PBK with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system; amino acids 1-322, 68kDa.
Description: This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.
Tissue specificity: Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules.
Biological activity: The Specific activity of PBK-29677TH was determined to be 6.2 nmol/min/mg.
Form: Liquid
Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase kinase subfamily.Contains 1 protein kinase domain.
Gene Name: PBK PDZ binding kinase [ Homo sapiens ]
Official Symbol: PBK
Synonyms: PBK; PDZ binding kinase; lymphokine-activated killer T-cell-originated protein kinase; cancer/testis antigen 84; CT84; FLJ14385; Nori 3; SPK; T LAK cell originated protein kinase; TOPK;
Gene ID: 55872
mRNA Refseq: NM_018492
Protein Refseq: NP_060962
MIM: 611210
Uniprot ID: Q96KB5
Chromosome Location: 8p21.2
Function: ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity;

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