Recombinant Human PHLDA2, T7 -tagged

• Cat.No.: PHLDA2-29671TH
• Product Overview: Recombinant full length protein (Human) with T7 tag at N terminus.

Specification

• Description: This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.
• Conjugation: T7
• Source: E. coli
• Tissue specificity: Expressed in placenta and adult prostate gland. In placenta, it is present in all cells of the villous cytotrophoblast. The protein is absent in cells from hydatidiform moles. Hydatidiform mole is a gestation characterized by abnormal development of both
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, 10mM DTT, pH 8
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the PHLDA2 family.Contains 1 PH domain.

Gene Information

• Gene Name: PHLDA2 pleckstrin homology-like domain, family A, member 2 [ Homo sapiens ]
• Official Symbol: PHLDA2
• Synonyms: PHLDA2; pleckstrin homology-like domain, family A, member 2; TSSC3, tumor suppressing subtransferable candidate 3; pleckstrin homology-like domain family A member 2; BWR1C; HLDA2; IPL
• Gene ID: 7262
• mRNA Refseq: NM_003311
• Protein Refseq: NP_003302
• MIM: 602131
• Uniprot ID: Q53GA4
• Chromosome Location: 11p15.4