"PHLDA2" Related Products


Recombinant Human PHLDA2, T7 -tagged

Cat.No.: PHLDA2-29671TH
Product Overview: Recombinant full length protein (Human) with T7 tag at N terminus.
Description: This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.
Conjugation: T7
Source: E. coli
Tissue specificity: Expressed in placenta and adult prostate gland. In placenta, it is present in all cells of the villous cytotrophoblast. The protein is absent in cells from hydatidiform moles. Hydatidiform mole is a gestation characterized by abnormal development of both
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton-X-100, 10mM Tris, 10mM DTT, pH 8
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Belongs to the PHLDA2 family.Contains 1 PH domain.
Gene Name: PHLDA2 pleckstrin homology-like domain, family A, member 2 [ Homo sapiens ]
Official Symbol: PHLDA2
Synonyms: PHLDA2; pleckstrin homology-like domain, family A, member 2; TSSC3, tumor suppressing subtransferable candidate 3; pleckstrin homology-like domain family A member 2; BWR1C; HLDA2; IPL;
Gene ID: 7262
mRNA Refseq: NM_003311
Protein Refseq: NP_003302
MIM: 602131
Uniprot ID: Q53GA4
Chromosome Location: 11p15.4

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