Recombinant Human PIK3CD

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Recombinant Human PIK3CD

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Cat.No. : PIK3CD-29587TH
Product Overview : Human Recombinant full length PI 3 Kinase p110 delta derived from Sf9 insect cells with tag, 120 kDa. The p85 alpha chain is 84 kDa.
Description : Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.
Tissue specificity : Expressed predominantly in leukocytes.
Biological activity : Activity: 3 nmol/mg/min using phosphatidylinositol as the substrate.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 50% Glycerol, 50mM Sodium chloride, 25mM Tris, 0.5mM Magnesium chloride, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the PI3/PI4-kinase family.Contains 1 PI3K/PI4K domain.
Gene Name : PIK3CD phosphoinositide-3-kinase, catalytic, delta polypeptide [ Homo sapiens ]
Official Symbol : PIK3CD
Synonyms : PIK3CD; phosphoinositide-3-kinase, catalytic, delta polypeptide; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; p110D; phosphatidylinositol 3 kinase; catalytic; delta polypeptide; phosphoinositide 3 kinase C;
Gene ID : 5293
mRNA Refseq : NM_005026
Protein Refseq : NP_005017
MIM : 602839
Uniprot ID : O00329
Chromosome Location : 1p36.2
Pathway : 3-phosphoinositide biosynthesis, conserved biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem;
Function : 1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-3-kinase activity; ATP binding; binding; kinase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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