Recombinant Human PIM2

• Cat.No.: PIM2-29589TH
• Product Overview: Recombinant full length PIM2 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 61kDa.

Specification

• Description: This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.
• Tissue specificity: Highly expressed in hematopoietic tissues, in leukemic and lymphoma cell lines, testis, small intestine, colon and colorectal adenocarcinoma cells. Weakly expressed in normal liver, but highly expressed in hepatocellular carcinoma tissues.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.Contains 1 protein kinase domain.

Gene Information

• Gene Name: PIM2 pim-2 oncogene [ Homo sapiens ]
• Official Symbol: PIM2
• Synonyms: PIM2; pim-2 oncogene; serine/threonine-protein kinase pim-2
• Gene ID: 11040
• mRNA Refseq: NM_006875
• Protein Refseq: NP_006866
• MIM: 300295
• Uniprot ID: Q9P1W9
• Chromosome Location: Xp11.23
• Pathway: Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem
• Function: ATP binding; nucleotide binding; protein serine/threonine kinase activity