Recombinant Human PITRM1, His-tagged

• Cat.No.: PITRM1-27541TH
• Product Overview: Recombinant fragment, corresponding to amino acids 364-1037 of Human PITRM1 with N terminal His tag; MWt 80 kDa.

Specification

• Description: Presequence protease, mitochondrial is an enzyme that in humans is encoded by the PITRM1 gene.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Widely expressed. Expressed at higher level in muscle and heart compared to brain, pancreas, liver, lung and placenta.
• Form: Lyophilised:Reconstitute with 58 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: ALIESGLGTDFSPDVGYNGYTREAY FSVGLQGIAEKDIET VRSLIDRTIDEVVEKGFEDDRIEAL LHKIEIQMKHQST SFGLMLTSYIASCWNHDGDPVELLK LGNQLAKFRQCLQ ENPKFLQEKVKQYFKNNQHKLTLSM RPDDKYHEKQAQVEA TKLKQKVEALSPGDRQQIYEKGLEL RSQQSKPQDASCL PALKVSDIEPTIPVTELDVVLTAGD IPVQYCAQPTNGM VYFRAFSSLNTLPEELRPYVPLFCS VLTKLGCGLLDYREQAQQIELKTGG MSASPHVLPDDSHMDTYEQGVLFSS LCL DRNLPDMMQLWSEIFNNPCFEEEEH FKVLVKMTAQELA NGIPDSGHLYASIRAGRTLTPAGDL QETFSGMDQVRLM KRIAEMTDIKPILRKLPRIKKHLLN GDNMRCSVNATPQQM PQTEKAVEDFLRSIGRSKKERRPVR PHTVEKPVPSSSG GDAHVPHGSQVIRKLVMEPTFKPWQ MKTHFLMPFPVNY VGECIRTVPYTDPDHASLKILARLM TAKFLHTEIREKGGAYGGGAKLSHN GIFTLYSYRDPNTIETLQSFGKAVD WAK SGKFTQQDIDEAKLSVFSTVDAPVA PSDKGMDHFLYGL SDEMKQAHREQLFAVSHDKLLAVSD RYLGTGKSTHGLA ILGPENPKIAKDPSWIIQ
• Sequence Similarities: Belongs to the peptidase M16 family. PreP subfamily.

Gene Information

• Gene Name: PITRM1 pitrilysin metallopeptidase 1 [ Homo sapiens ]
• Official Symbol: PITRM1
• Synonyms: PITRM1; pitrilysin metallopeptidase 1; pitrilysin metalloproteinase 1; presequence protease, mitochondrial; hMP1; KIAA1104; MP1; PreP; PreP peptidasome
• Gene ID: 10531
• mRNA Refseq: NM_001242307
• Protein Refseq: NP_001229236
• Uniprot ID: Q5JRX3
• Chromosome Location: 10p15.2
• Function: enzyme activator activity; metal ion binding; metalloendopeptidase activity; peptidase activity; zinc ion binding