"PLAT" Related Products

Expand
Expand
Expand

Native Human Human SERPINE1

Cat.No.: PLAT-29690TH
Product Overview: Full length Human PAI1 purified from E. coli reacted with full length Human PLAT purified from CHO cells; MWt 113kDa.
Description: This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 0.4M HEPES, 0.1M Sodium chloride, pH 7.4
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name: PLAT plasminogen activator, tissue [ Homo sapiens ]
Official Symbol: PLAT
Synonyms: PLAT; plasminogen activator, tissue; tissue-type plasminogen activator;
Gene ID: 5327
mRNA Refseq: NM_000930
Protein Refseq: NP_000921
MIM: 173370
Uniprot ID: P00750
Chromosome Location: 8p11.21
Pathway: Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Dissolution of Fibrin Clot, organism-specific biosystem;
Function: peptidase activity; protein binding; serine-type endopeptidase activity; serine-type endopeptidase activity;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.