"ALAS2" Related Products


Recombinant Human Aminolevulinate, Delta-, Synthase 2, His-tagged

Cat. No.: ALAS2-419H
Product Overview: Recombinant Human ALAS (aminolevulinate, delta-, synthase 2) (a.a. 136-553) with N-terminal His tag, MW = 46 kDa, expressed in anE.Coliexpression system.
Description: Delta-aminolevulinate synthase 2 also known as ALAS2 is a protein which in humans is encoded by the ALAS2 gene. ALAS2 is an aminolevulinic acid synthase.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Source: E.Coli.
Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, 3 mM DTT, 20 μM pyridoxal 5' phosphate monohydrate.
Purity: 90%.
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Stability: >6 months at -80°C.
Gene Name: ALAS2 aminolevulinate, delta-, synthase 2 [ Homo sapiens ]
Synonyms: ALAS2; aminolevulinate, delta-, synthase 2; ASB; ANH1; XLSA; ALASE; ALAS-E; FLJ93603; 5-aminolevulinate synthase 2; delta-ALA synthetase; 5-aminolevulinic acid synthase; delta-aminolevulinate synthase; 5-aminolevulinate synthase, erythroid-specific, mitochondrial; EC;aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia); OTTHUMP00000023388; OTTHUMP00000023389
Gene ID: 212
mRNA Refseq: NM_000032
Protein Refseq: NP_000023
MIM: 301300
UniProt ID: P22557
Chromosome Location: Xp11.21
Pathway: Glycine, serine and threonine metabolism; Metabolic pathways; Porphyrin and chlorophyll metabolism
Function: 5-aminolevulinate synthase activity; acyltransferase activity; coenzyme binding; glycine binding; protein binding; pyridoxal phosphate binding; transferase activity, transferring nitrogenous groups

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.