||Recombinant Human ALAS (aminolevulinate, delta-, synthase 2) (a.a. 136-553) with N-terminal His tag, MW = 46 kDa, expressed in anE.Coliexpression system.
||Delta-aminolevulinate synthase 2 also known as ALAS2 is a protein which in humans is encoded by the ALAS2 gene. ALAS2 is an aminolevulinic acid synthase.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
||25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, 3 mM DTT, 20 μM pyridoxal 5' phosphate monohydrate.
||Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
||>6 months at -80°C.