Recombinant Human ARAF protein, His/GST-tagged ARAF-504H

Recombinant Human ARAF protein, His/GST-tagged

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Recombinant Human ARAF protein, His/GST-tagged

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Cat.No. : ARAF-504H
Product Overview : Recombinant Human ARAF(282–606) fused with GST tag at N-terminal and His tag at C-terminal was expressed in Insect cells.
Description : This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : Insect cells
Species : Human
Tag : His/GST
Form : 40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween-20, 20% glycerol and 3 mM DTT.
Bio-activity : 40 pmol/min/µg
Molecular Mass : 63 kDa
Applications : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Storage : >6 months at -80 centigrade. Avoid freeze/thaw cycles.
Concentration : 0.46 mg/ml
Gene Name : ARAF v-raf murine sarcoma 3611 viral oncogene homolog [ Homo sapiens ]
Official Symbol : ARAF
Synonyms : ARAF; v-raf murine sarcoma 3611 viral oncogene homolog; ARAF1, v raf murine sarcoma 3611 viral oncogene homolog 1; serine/threonine-protein kinase A-Raf; Oncogene ARAF1; proto-oncogene Pks; proto-oncogene A-Raf-1; Ras-binding protein DA-Raf; v-raf murine sarcoma 3611 viral oncogene homolog 1; A-Raf proto-oncogene serine/threonine-protein kinase; PKS2; A-RAF; ARAF1; RAFA1;
Gene ID : 369
mRNA Refseq : NM_001654
Protein Refseq : NP_001645
MIM : 311010
UniProt ID : P10398
Chromosome Location : Xp11.3-p11.23
Pathway : Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem; Colorectal cancer, organism-specific biosystem;
Function : ATP binding; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity; receptor signaling protein activity;

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