"CARM1" Related Products


Recombinant Human CARM1

Cat. No. : CARM1-451H
Product Overview : Recombinant Human PRMT4, amino-acids 2-end expressed in aFreeStyle 293-F cellsexpression system. MW= 66 kDa.
Description : CARM1 (coactivator-associated arginine methyltransferase 1) is an enzyme encoded by the CARM1 gene found in human beings, as well as many other mammals. CARM1 is a secondary coactivator through its association with p160 family (SRC-1, GRIP1, AIB) of coactivators. It is responsible for moving cells toward the inner cell mass in developing blastocysts. This gene also plays an important role in androgen receptors and may play a role in prostate cancer progression.
Source : FreeStyle 293-F cells.
Purity : >60%.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT.
Stability : >6 months at –80°C.
Gene Name : CARM1 coactivator-associated arginine methyltransferase 1 [ Homo sapiens ]
Synonyms : CARM1; coactivator-associated arginine methyltransferase 1; PRMT4;EC; 3` partial; protein arginine N-methyltransferase 4; Histone-arginine methyltransferase CARM1;EC2.1.1.-; Protein arginine N-methyltransferase 4; Coactivator-associated arginine methyltransferase 1
Gene ID : 10498
mRNA Refseq : NM_199141
Protein Refseq : NP_954592
MIM : 603934
UniProt ID : Q86X55
Chromosome Location : 19p13.2
Pathway : Metabolism of lipids and lipoproteins
Function : histone-arginine N-methyltransferase activity; transferase activity; protein binding; transcription coactivator activity; protein methyltransferase activity

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