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Recombinant Human POLL, His-tagged

Cat.No. : POLL-28363TH
Product Overview : Recombinant full length human DNA Polymerase lambda with a N terminal His tag. Mw: 36kDa.
  • Specification
  • Gene Information
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Description : This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described.
Protein length : 320 amino acids
Conjugation : HIS
Molecular Weight : 36.000kDa
Source : E. coli
Tissue specificity : Expressed in a number of tissues. Abundant in testis.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : pH: 8.00Constituents:0.02% DTT, 0.32% Tris HCl, 0.58% Sodium chloride, 30% Glycerol
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH TKTAQMWYQQ GFRSLEDIRS QASLTTQQAI GLKHYSDFLE RMPREEATEI EQTVQKAAQA FNSGLLCVAC GSYRRGKATC GDVDVLITHP DGRSHRGIFS RLLDSLRQEG FLTDDLVSQE ENGQQQKYLG VCRLPGPGRR HRRLDIIVVP YSEFACALLY FTGSAHFNRS MRALAKTKGM MLMHHQKYLQ RFLGGKREKK QKEACSIPGI GKRMAEKIIE ILESGHLRKL DHISESVPVL ELFSNIWGAG SLSEHALSTA VVRNTHGCKV GPGRVLPTPT EKDVFRLLGL PYREPAERDW
Sequence Similarities : Belongs to the DNA polymerase type-X family.Contains 1 BRCT domain.
Gene Name : POLL polymerase (DNA directed), lambda [ Homo sapiens ]
Official Symbol : POLL
Synonyms : POLL; polymerase (DNA directed), lambda; DNA polymerase lambda;
Gene ID : 27343
mRNA Refseq : NM_001174084
Protein Refseq : NP_001167555
MIM : 606343
Uniprot ID : Q9UGP5
Chromosome Location : 10q23
Pathway : BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Non-homologous end-joining, organism-specific biosystem;
Function : DNA binding; DNA binding; DNA-directed DNA polymerase activity; DNA-directed DNA polymerase activity; catalytic activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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