Recombinant Human Cathepsin L2, His-tagged CTSL2-507H

Recombinant Human Cathepsin L2, His-tagged

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Recombinant Human Cathepsin L2, His-tagged

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Cat. No. : CTSL2-507H
Product Overview : Recombinant Human cathepsin V, CD33 signal peptide(1-16aa) + cathepsin V (a-a 18-334), with C-terminal His tag expressed inFreeStyle 293-F cells. MW= 37 kDa.
Description : The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes.
Source : FreeStyle 293-F cells.
Purity : >90%.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20 and 10% glycerol.
Stability : >6 months at –80°C.
PDB rendering based on 1fh0. :

Gene Name : CTSL2 cathepsin L2 [ Homo sapiens ]
Synonyms : CTSL2; cathepsin L2; CTSU; CTSV; CATL2; MGC125957;EC3.4.22.43; Cathepsin L2; Cathepsin V; Cathepsin U; UNQ268/PRO305
Gene ID : 1515
mRNA Refseq : NM_001333
Protein Refseq : NP_001324
MIM : 603308
UniProt ID : O60911
Chromosome Location : 9q22.2
Pathway : Lysosome
Function : cysteine-type endopeptidase activity; peptidase activity; protein binding

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