Recombinant Human PPP6C

• Cat.No.: PPP6C-29541TH
• Product Overview: Recombinant full length Human PPP6C with N terminal proprietary tag; Predicted MW 59.29 kDa.

Specification

• Description: This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X.
• Protein length: 305 amino acids
• Molecular Weight: 59.290kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESN VQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMG DFVDSGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT QVYGFYDECQTKYGNANAWRYCTKVLDMLTVAALIDEQIL CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPE DVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTR EPKLFRAVPDSERVIPPRTTTPYFL
• Sequence Similarities: Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily.

Gene Information

• Gene Name: PPP6C protein phosphatase 6, catalytic subunit [ Homo sapiens ]
• Official Symbol: PPP6C
• Synonyms: PPP6C; protein phosphatase 6, catalytic subunit; serine/threonine-protein phosphatase 6 catalytic subunit; PP6
• Gene ID: 5537
• mRNA Refseq: NM_001123355
• Protein Refseq: NP_001116827
• MIM: 612725
• Uniprot ID: O00743
• Chromosome Location: 9q33.3
• Function: hydrolase activity; metal ion binding; protein binding; protein serine/threonine phosphatase activity