Recombinant Human PRDX4, His-tagged
Cat.No. : | PRDX4-30466TH |
Product Overview : | Recombinant full length Human Peroxiredoxin 4 with N terminal His tag; 255 amino acids with tag, MWt 28.8 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. |
Conjugation : | HIS |
Source : | E. coli |
Biological activity : | Specific activity: approximately 230-310 pmole/min/μg.Enzymatic activity was confirmed by measuring the remaining peroxide after incubation of PRDX4 and peroxide for 20 min at room temperature. Specific activity is defined as the amount of hydroperoxide t |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the ahpC/TSA family.Contains 1 thioredoxin domain. |
Gene Name : | PRDX4 peroxiredoxin 4 [ Homo sapiens ] |
Official Symbol : | PRDX4 |
Synonyms : | PRDX4; peroxiredoxin 4; peroxiredoxin-4; AOE37 2; |
Gene ID : | 10549 |
mRNA Refseq : | NM_006406 |
Protein Refseq : | NP_006397 |
MIM : | 606506 |
Uniprot ID : | Q13162 |
Chromosome Location : | X |
Pathway : | Selenium Pathway, organism-specific biosystem; |
Function : | oxidoreductase activity; thioredoxin peroxidase activity; |
Products Types
◆ Recombinant Protein | ||
PRDX4-322H | Recombinant Human PRDX4 Protein, His-tagged | +Inquiry |
PRDX4-1759H | Recombinant Human PRDX4 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRDX4-2845H | Recombinant Human PRDX4 protein(71-260 aa), C-His-tagged | +Inquiry |
Prdx4-323M | Recombinant Mouse Prdx4 Protein, His-tagged | +Inquiry |
PRDX4-3410R | Recombinant Rhesus Macaque PRDX4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PRDX4-2880HCL | Recombinant Human PRDX4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionPRDX4 acts as a peroxidase, reducing peroxides to protect cells from oxidative stress.
It assists in protein folding and prevents the aggregation of misfolded proteins.
PRDX4 is primarily located in the endoplasmic reticulum and secreted extracellularly.
Therapeutic applications may involve modulating PRDX4 activity to mitigate oxidative stress-related diseases.
It reduces hydrogen peroxide and lipid peroxides, contributing to the antioxidant defense.
Cellular redox status and covalent modifications regulate PRDX4 activity.
PRDX4 deficiency can lead to increased oxidative stress and damage, affecting cellular functions.
Customer Reviews (3)
Write a reviewDelivery on time, perfect.
Very effective protein product.
High-quality, great for research.
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