Recombinant Human PRPF19, His-tagged

• Cat.No.: PRPF19-30592TH
• Product Overview: Recombinant fragment, corresponding to amino acids 235-504 of Human PRP19 with an N terminal His tag. Predicted mwt: 31 kDa

Specification

• Description: PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair (Beck et al.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 118 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: NKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHP SQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGL SLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSG CSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG HSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFK TLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWT EILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL

Gene Information

• Gene Name: PRPF19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: PRPF19
• Synonyms: PRPF19; PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae); PRP19, PRP19/PSO4 homolog (S. cerevisiae); pre-mRNA-processing factor 19; hPSO4; NMP200; nuclear matrix protein NMP200 related to splicing factor PRP19; PSO4; UBOX4
• Gene ID: 27339
• mRNA Refseq: NM_014502
• Protein Refseq: NP_055317
• MIM: 608330
• Uniprot ID: Q9UMS4
• Chromosome Location: 11q12.2
• Pathway: Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; Spliceosome, 35S U5-snRNP, organism-specific biosystem; Spliceosome, Prp19/CDC5L complex, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem
• Function: DNA binding; identical protein binding; protein binding; ubiquitin-protein ligase activity; ubiquitin-ubiquitin ligase activity