Recombinant Human PTGS2, His-tagged
Cat.No. : | PTGS2-26360TH |
Product Overview : | Recombinant full length COX2 / Cyclooxygenase 2 protein (Human), a homodimer (70-74 kDa/subunit), contains a six histidine tag near the N-terminus.Isolated from a Baculovirus overexpression system in Sf 21 cells. |
- Specification
- Gene Information
- Related Products
Description : | Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. |
Conjugation : | HIS |
Biological activity : | Specific Activity: minimum 8,000 units per mg protein |
Form : | Liquid |
Storage buffer : | Preservative: 300μM diethyldithio-carbamate (DDC)Constituents: 0.1% Tween 20, 80mM Tris HCl, pH 8Note: If this preservative (DDC) is undesirable, it can be removed by standard desalting procedures, but the enzyme is unstable in the absence of the preserva |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the prostaglandin G/H synthase family.Contains 1 EGF-like domain. |
Gene Name : | PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) [ Homo sapiens ] |
Official Symbol : | PTGS2 |
Synonyms : | PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); prostaglandin G/H synthase 2; COX2; |
Gene ID : | 5743 |
mRNA Refseq : | NM_000963 |
Protein Refseq : | NP_000954 |
MIM : | 600262 |
Uniprot ID : | P35354 |
Chromosome Location : | 1q25.2-q25.3 |
Pathway : | Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Biological oxidations, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; COX reactions, organism-specific biosystem; |
Function : | enzyme binding; heme binding; lipid binding; metal ion binding; oxidoreductase activity; |
Products Types
◆ Recombinant Protein | ||
PTGS2-752H | Recombinant Human PTGS2 Protein (18-601 aa), His-tagged | +Inquiry |
PTGS2-01H | Active Recombinant Human PTGS2 2N580A Mutant Protein, His-tagged | +Inquiry |
PTGS2-857H | Recombinant Human PTGS2 protein(Met1-Leu604), His-tagged | +Inquiry |
PTGS2-63H | Recombinant Human PTGS2 Protein, His-tagged | +Inquiry |
PTGS2-080H | Active Recombinant Human PTGS2 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
PTGS2-57S | Native Sheep PTGS2 Protein | +Inquiry |
◆ Lysates | ||
PTGS2-643HCL | Recombinant Human PTGS2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket