Recombinant Human PTPMT1, His-tagged

• Cat.No.: PTPMT1-31117TH
• Product Overview: Recombinant full length Human PTPMT1 with N terminal His tag; 199 amino acids with tag, Predicted MWt 22.6 kDa.

Specification

• Description: This protein phosphatase specifically mediates the dephosphorylation of mitochondrial proteins and consequently plays a central role in ATP production.
• Protein length: 174 amino acids
• Conjugation: HIS
• Molecular Weight: 22.600kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 10% Glycerol, 0.02% DTT, 0.88% Sodium chloride
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGSHMKVPGRAHRDWYHRID PTVLLGALPLRSLTRQLVQDENVRGVITMNEEYETRFLCN SSQEWKRLGVEQLRLSTVDMTGIPTLDNLQKGVQFALKYQ SLGQCVYVHCKAGRSRSATMVAAYLIQVHKWSPEEAVRAI AKIRSYIHIRPGQLDVLKEFHKQITARATKDGTFVISKT
• Sequence Similarities: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.Contains 1 tyrosine-protein phosphatase domain.

Gene Information

• Gene Name: PTPMT1 protein tyrosine phosphatase, mitochondrial 1 [ Homo sapiens ]
• Official Symbol: PTPMT1
• Synonyms: PTPMT1; protein tyrosine phosphatase, mitochondrial 1; protein-tyrosine phosphatase mitochondrial 1; DUSP23; MOSP; PLIP
• Gene ID: 114971
• mRNA Refseq: NM_001143984
• Protein Refseq: NP_001137456
• MIM: 609538
• Uniprot ID: Q8WUK0
• Chromosome Location: 11p11.2
• Pathway: 3-phosphoinositide degradation, conserved biosystem
• Function: hydrolase activity; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity