Recombinant Human PXN


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Recombinant Human PXN

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Cat.No. : PXN-29060TH
Product Overview : Recombinant fragment of Human Paxillin (amino acids 356-558) withproprietary tag; 203aa (without tag), 48kDa.
Description : This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
Protein length : 203 amino acids
Molecular Weight : 48.000kDa inclusive of tags
Source : E. coli
Form : Liquid
Storage buffer : pH: 7.50Constituents:Tris acetate, 20% Glycerol, 0.03% EDTA
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the paxillin family.Contains 4 LIM zinc-binding domains.
Gene Name : PXN paxillin [ Homo sapiens ]
Official Symbol : PXN
Synonyms : PXN; paxillin;
Gene ID : 5829
mRNA Refseq : NM_001080855
Protein Refseq : NP_001074324
MIM : 602505
Uniprot ID : P49023
Chromosome Location : 12q24
Pathway : Androgen Receptor Signaling Pathway, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Arf6 signaling events, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem;
Function : beta-catenin binding; metal ion binding; protein binding; vinculin binding; zinc ion binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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