Recombinant Human QPRT, His-tagged
Cat.No. : | QPRT-30232TH |
Product Overview : | Recombinant full length Human QPRT with a N terminal His tag; 317aa inclusive of tag, 32.9 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimers disease, and Huntingtons disease. |
Protein length : | 297 amino acids |
Conjugation : | HIS |
Molecular Weight : | 32.900kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: 0% NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMDAEG LALLLPPVTLAALVDSWLREDCPGL NYAALVSGAGPSQAALWAKSPGVLA GQPFFDAIFTQLNCQVSWFLPEGSK LVPVARVAEVRGPAHCLLLGERVAL NTLARCSGIASAAAAAVEAARGAGW TGHVAGTRKTTPGFRLVEKYGLLVG GAASHRYDLGGLVMVKDNHVVAAGG VEKAVRAARQAADFALKVEVECSSL QEAVQAAEAGADLVLLDNFKPEELH PTATVLKAQFPSVAVEASGGITLDN LPQFCGPHIDVISMGMLTQAAPALD FSLKLFAKEVAPVPKIH |
Sequence Similarities : | Belongs to the nadC/modD family. |
Gene Name : | QPRT quinolinate phosphoribosyltransferase [ Homo sapiens ] |
Official Symbol : | QPRT |
Synonyms : | QPRT; quinolinate phosphoribosyltransferase; nicotinate-nucleotide pyrophosphorylase [carboxylating]; nicotinate nucleotide pyrophosphorylase (carboxylating); QPRTase; |
Gene ID : | 23475 |
mRNA Refseq : | NM_014298 |
Protein Refseq : | NP_055113 |
MIM : | 606248 |
Uniprot ID : | Q15274 |
Chromosome Location : | 16p11.2 |
Pathway : | Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; |
Function : | nicotinate-nucleotide diphosphorylase (carboxylating) activity; protein homodimerization activity; |
Products Types
◆ Recombinant Protein | ||
QPRT-7324M | Recombinant Mouse QPRT Protein, His (Fc)-Avi-tagged | +Inquiry |
Qprt-5280M | Recombinant Mouse Qprt Protein, Myc/DDK-tagged | +Inquiry |
QPRT-4523R | Recombinant Rat QPRT Protein, His (Fc)-Avi-tagged | +Inquiry |
QPRT-2814H | Recombinant Human Quinolinate Phosphoribosyltransferase, His-tagged | +Inquiry |
QPRT-30231TH | Recombinant Human QPRT, T7 -tagged | +Inquiry |
◆ Lysates | ||
QPRT-2637HCL | Recombinant Human QPRT 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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