| Cat.No. : |
RXRA-31121TH |
| Product Overview : |
Recombinant fragment corresponding to amino acids 200-462 of Human Retinoid X Receptor alpha with His tag, 30 kDa. |
| Description : |
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation.These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. |
| Conjugation : |
HIS |
| Source : |
E. coli |
| Tissue specificity : |
Highly expressed in liver, also found in lung, kidney and heart. |
| Biological activity : |
1 unit equals 1 nanogram purified protein. |
| Form : |
Liquid |
| Purity : |
>95% by SDS-PAGE |
| Storage buffer : |
Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0 |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequence Similarities : |
Belongs to the nuclear hormone receptor family. NR2 subfamily.Contains 1 nuclear receptor DNA-binding domain. |
