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Recombinant Human RXRB, His-tagged

Cat.No.: RXRB-31124TH
Product Overview: Recombinant full length Human Retinoid X Receptor beta with His tag expressed in a baculovirus system under the control of a T7 promoter, approximately 57kDa, amino acids 1-533,
Description: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Conjugation: HIS
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name: RXRB retinoid X receptor, beta [ Homo sapiens ]
Official Symbol: RXRB
Synonyms: RXRB; retinoid X receptor, beta; retinoic acid receptor RXR-beta; H 2RIIBP; NR2B2; RCoR 1;
Gene ID: 6257
mRNA Refseq: NM_021976
Protein Refseq: NP_068811
MIM: 180246
Uniprot ID: P28702
Chromosome Location: 6p21.3
Pathway: Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Non-small cell lung cancer, organism-specific biosystem;
Function: ligand-regulated transcription factor activity; metal ion binding; protein binding; protein heterodimerization activity; receptor activity;

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