Recombinant Human RXRB, His-tagged
Cat.No. : | RXRB-31124TH |
Product Overview : | Recombinant full length Human Retinoid X Receptor beta with His tag expressed in a baculovirus system under the control of a T7 promoter, approximately 57kDa, amino acids 1-533, |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. |
Conjugation : | HIS |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Gene Name : | RXRB retinoid X receptor, beta [ Homo sapiens ] |
Official Symbol : | RXRB |
Synonyms : | RXRB; retinoid X receptor, beta; retinoic acid receptor RXR-beta; H 2RIIBP; NR2B2; RCoR 1; |
Gene ID : | 6257 |
mRNA Refseq : | NM_021976 |
Protein Refseq : | NP_068811 |
MIM : | 180246 |
Uniprot ID : | P28702 |
Chromosome Location : | 6p21.3 |
Pathway : | Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Non-small cell lung cancer, organism-specific biosystem; |
Function : | ligand-regulated transcription factor activity; metal ion binding; protein binding; protein heterodimerization activity; receptor activity; |
Products Types
◆ Recombinant Protein | ||
RXRB-0970H | Recombinant Human RXRB Protein (G294-A528), Tag Free | +Inquiry |
RXRB-0971H | Recombinant Human RXRB Protein (G294-A528), His tagged | +Inquiry |
RXRB-31125TH | Recombinant Human RXRB | +Inquiry |
RXRB-1154H | Active Recombinant Human Retinoid X Receptor, Beta, GST-tagged | +Inquiry |
RXRB-2514H | Active Recombinant Human Retinoid X Receptor, Beta, His-tagged | +Inquiry |
◆ Lysates | ||
RXRB-2098HCL | Recombinant Human RXRB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionEnvironmental factors like diet and sunlight alter RXRB activity, impacting its role in skin health and metabolic processes.
Dysregulation of RXRB can contribute to the development and progression of various cancers.
RXRB modulates the immune system, affecting autoimmune and inflammatory responses.
RXRB is crucial in lipid metabolism, influencing processes related to obesity and metabolic health.
RXRB plays a key role in maintaining skin health and is involved in the pathology of skin disorders.
RXRB impacts neurodevelopment and is implicated in the progression of neurodegenerative diseases.
RXRB binds retinoic acid and other ligands to regulate genes involved in development, metabolism, and cell differentiation.
Customer Reviews (3)
Write a reviewTimely support for protein expression optimization, appreciated assistance.
High-quality protein characterization, fundamental for our research.
Accurate protein structural analysis, indispensable for our investigations.
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