Recombinant Human SELL, His-tagged
Cat.No. : | SELL-27884TH |
Product Overview : | Recombinant fragment correspondingn to the mature form of human CD62L (aminoacids 39/332 of the precursor) with an N-termial hexahistidine tag |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Expressed in B cell lines and T lymphocytes. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, 20mM Tris, pH 8 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | WT YHYSEKPMNW QRARRFCRDN YTDLVAIQNK AEIEYLEKTL PFSRSYYWIG IRKIGGIWTW VGTNKSLTEE AENWGDGEPN NKKNKEDCVE IYIKRNKDAG KWNDDACHKL KAALCYTASC QPWSCSGHGE CVEIINNYTC NCDVGYYGPQ CQFVIQCEPL EAPELGTMDC THPLGNFSFS SQCAFSCSEG TNLTGIEETT CGPFGNWSSP EPTCQVIQCE PLSAPDLGIM NCSHPLASFS FTSACTFICS EGTELIGKKK TICESSGIWS NPSPICQKLD KS |
Sequence Similarities : | Belongs to the selectin/LECAM family.Contains 1 C-type lectin domain.Contains 1 EGF-like domain.Contains 2 Sushi (CCP/SCR) domains. |
Gene Name : | SELL selectin L [ Homo sapiens ] |
Official Symbol : | SELL |
Synonyms : | SELL; selectin L; LNHR, LYAM1, lymphocyte adhesion molecule 1; L-selectin; CD62L; hLHRc; LAM 1; LAM1; Leu 8; LSEL; Lyam 1; PLNHR; |
Gene ID : | 6402 |
mRNA Refseq : | NM_000655 |
Protein Refseq : | NP_000646 |
MIM : | 153240 |
Uniprot ID : | P14151 |
Chromosome Location : | 1q23-q25 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function : | carbohydrate binding; cell adhesion molecule binding; glycosphingolipid binding; heparin binding; protease binding; |
Products Types
◆ Recombinant Protein | ||
SELL-227H | Recombinant Human SELL Protein, His-tagged | +Inquiry |
Sell-165M | Recombinant Mouse Sell Protein, His (Fc)-Avi-tagged | +Inquiry |
Sell-5756M | Recombinant Mouse Sell Protein, His-tagged | +Inquiry |
SELL-233H | Recombinant Human SELL Protein, His (Fc)-Avi-tagged | +Inquiry |
SELL-3949R | Recombinant Rhesus Macaque SELL Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SELL-1963HCL | Recombinant Human SELL cell lysate | +Inquiry |
SELL-2614MCL | Recombinant Mouse SELL cell lysate | +Inquiry |
SELL-1131CCL | Recombinant Cynomolgus SELL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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