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Native Human SERPINA3

Cat.No.: SERPINA3-27285TH
Product Overview: Full length Human alpha 1 Antichymotrypsin from plasma, 45 kDa.
Description: The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this proteins sequence have been implicated in Alzheimers disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Source: human plasma
Species: Human
Form: Liquid
Molecular Mass: 45 kDa
Purity: >95% by SDS-PAGE
Storage: Shipped at 4°C . Upon delivery aliquot and store at -20°C or -80°C . Avoid repeated freeze / thaw cycles.
Storage Buffer: Preservative: NoneConstituents: 20mM Tris, 150mM Sodium chloride, pH 7.4
Gene Name: SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 [ Homo sapiens ]
Official Symbol: SERPINA3
Synonyms: SERPINA3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; AACT, alpha 1 antichymotrypsin , serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 3; alpha-1-antichymotrypsin;
Gene ID: 12
mRNA Refseq: NM_001085
Protein Refseq: NP_001076
MIM: 107280
UniProt ID: P01011
Chromosome Location: 14q32.1
Pathway: Selenium Pathway, organism-specific biosystem;
Function: DNA binding; peptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity;

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