Recombinant Mouse Matrix Metallopeptidase 2
Cat.No. : | Mmp2-415M |
- Specification
- Gene Information
- Related Products
Cat. No. : | Mmp2-415M |
Description : | Matrix metallopeptidase 2, also known as MMP2, is an enzyme involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP"s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP-2 degrades type IV collagen, the major structural component of basement membranes and plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. MMP2 has been found to be associated with tumor invasion in various cancers. |
Molecular Weight : | The molecular weight of Recombinant Mouse MMP-2 is Mr 72 kDa. |
Source : | Mammalian cells |
State Of Matter : | Solution. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Formulation : | Supplied as a 0.2 μm filtered solution of 25 mM Tris, pH 7.5, 5 mM CaCl2, 75 mM NaCl, 0.025% Brij-35 and 50% glycerol at a concentration of 0.113 mg/mL. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Biological Activity : | The specific activity, measured under the described conditions, is > 1,500 pmoles/min/μg. |
Storage And Stability : | This protein is stable for one month when stored sterile at -20°C or for three months when stored at -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Gene Name : | Mmp2 matrix metallopeptidase 2 [ Mus musculus ] |
Synonyms : | Mmp2; matrix metallopeptidase 2; GelA; Clg4a; MMP-2; gelatinase A; 72kD gelatinase; 72kDa gelatinase; 72kD type IV collagenase; 72kDa type IV collagenase; matrix metalloproteinase-2; EC 3.4.24.24 |
Gene ID : | 17390 |
mRNA Refseq : | NM_008610 |
Protein Refseq : | NP_032636 |
UniProt ID : | P33434 |
Chromosome Location : | 8 C5; 8 44.0 cM |
Pathway : | Bladder cancer; GnRH signaling pathway; Leukocyte transendothelial migration; Pathways in cancer |
Function : | calcium ion binding; hydrolase activity; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
MMP2-1121H | Recombinant Human MMP2 Protein, His-tagged | +Inquiry |
MMP2-03H | Active Recombinant Pre-activated Human MMP2 Protein (110-660) | +Inquiry |
MMP2-5425H | Recombinant Human MMP2 Protein, GST-tagged | +Inquiry |
Mmp2-4100M | Recombinant Mouse Mmp2 Protein, Myc/DDK-tagged | +Inquiry |
MMP2-1120H | Recombinant Human MMP2 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
MMP2-29475TH | Native Human MMP2 | +Inquiry |
MMP2-47H | Native Human MMP-2/TIMP-2 Complex | +Inquiry |
MMP2-8455M | Native Mouse MMP2 | +Inquiry |
◆ Lysates | ||
MMP2-2380HCL | Recombinant Human MMP2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0320C | MMP2 Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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