|Cat. No. :
||Matrix metallopeptidase 2, also known as MMP2, is an enzyme involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP"s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP-2 degrades type IV collagen, the major structural component of basement membranes and plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. MMP2 has been found to be associated with tumor invasion in various cancers.
|Molecular Weight :
||The molecular weight of Recombinant Mouse MMP-2 is Mr 72 kDa.
|State Of Matter :
||>95% by SDS Page and analyzed by silver stain.
||Supplied as a 0.2 μm filtered solution of 25 mM Tris, pH 7.5, 5 mM CaCl2, 75 mM NaCl, 0.025% Brij-35 and 50% glycerol at a concentration of 0.113 mg/mL.
||<1.0 EU/µg as determined by the LAL method.
|Biological Activity :
||The specific activity, measured under the described conditions, is > 1,500 pmoles/min/μg.
|Storage And Stability :
||This protein is stable for one month when stored sterile at -20°C or for three months when stored at -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.