"SIRT6" Related Products

Expand
Expand
Expand

Recombinant Human SIRT6, T7 -tagged

Cat.No.: SIRT6-28517TH
Product Overview: Recombinant full length Human SIRT6 with N-terminal proprietary tag, 65 kDa.
Description: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
Conjugation: T7
Source: E. coli
Form: Liquid
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 0.05% Tween 20, 25mM Tris HCl, 100mM Sodium chloride, pH 8
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the sirtuin family.Contains 1 deacetylase sirtuin-type domain.
Gene Name: SIRT6 sirtuin 6 [ Homo sapiens ]
Official Symbol: SIRT6
Synonyms: SIRT6; sirtuin 6; sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 6; NAD-dependent deacetylase sirtuin-6;
Gene ID: 51548
mRNA Refseq: NM_016539
Protein Refseq: NP_057623
MIM: 606211
Uniprot ID: Q8N6T7
Chromosome Location: 19p13.3
Pathway: Signaling events mediated by HDAC Class I, organism-specific biosystem;
Function: NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD+ ADP-ribosyltransferase activity; NAD+ binding; NAD-dependent histone deacetylase activity; NAD-dependent histone deacetylase activity (H3-K9 specific);

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.