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Recombinant Human SIRT7, T7 -tagged

Cat.No. : SIRT7-30848TH
Product Overview : Recombinant full length Human SIRT7 , with N terminal proprietary tag.
Description : This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
Conjugation : T7
Source : E. coli
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 0.05% Tween 20, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Belongs to the sirtuin family.Contains 1 deacetylase sirtuin-type domain.
Gene Name : SIRT7 sirtuin 7 [ Homo sapiens ]
Official Symbol : SIRT7
Synonyms : SIRT7; sirtuin 7; sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7; NAD-dependent deacetylase sirtuin-7;
Gene ID : 51547
mRNA Refseq : NM_016538
Protein Refseq : NP_057622
MIM : 606212
Uniprot ID : Q9NRC8
Chromosome Location : 17q25.3
Pathway : Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class III, organism-specific biosystem;
Function : NAD+ binding; hydrolase activity; metal ion binding; protein binding; zinc ion binding;

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