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Recombinant Human SIRT7, His-tagged
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Cat.No. : | SIRT7-30867TH |
Product Overview : | Recombinant full length Human SIRT7 with N terminal His tag; MWt 46 kDa. |
Description : | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. |
Protein length : | 400 amino acids |
Conjugation : | HIS |
Molecular Weight : | 46.000kDa inclusive of tags |
Source : | Baculovirus infected sf9 cells |
Biological activity : | The Specific activity of SIRT7-30867TH was determined to be 140 RLU/min/ng. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: 150mM ImidazoleConstituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.0 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the sirtuin family.Contains 1 deacetylase sirtuin-type domain. |
Gene Name : | SIRT7 sirtuin 7 [ Homo sapiens ] |
Official Symbol : | SIRT7 |
Synonyms : | SIRT7; sirtuin 7; sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) , sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7; NAD-dependent deacetylase sirtuin-7; |
Gene ID : | 51547 |
mRNA Refseq : | NM_016538 |
Protein Refseq : | NP_057622 |
MIM : | 606212 |
Uniprot ID : | Q9NRC8 |
Chromosome Location : | 17q25.3 |
Pathway : | Signaling events mediated by HDAC Class I, organism-specific biosystem; Signaling events mediated by HDAC Class III, organism-specific biosystem; |
Function : | NAD+ binding; hydrolase activity; metal ion binding; protein binding; zinc ion binding; |
◆ Recombinant Protein
Sirt7-5886M | Recombinant Mouse Sirt7 Protein, Myc/DDK-tagged | +Inquiry |
SIRT7-21H | Recombinant Human SIRT7 Protein, His-tagged | +Inquiry |
SIRT7-30848TH | Recombinant Human SIRT7, T7 -tagged | +Inquiry |
SIRT7-4207R | Recombinant Rhesus monkey SIRT7 Protein, His-tagged | +Inquiry |
SIRT7-5512C | Recombinant Chicken SIRT7 | +Inquiry |
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◆ Lysates
SIRT7-1828HCL | Recombinant Human SIRT7 293 Cell Lysate | +Inquiry |
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