Recombinant Human SNPH, His-tagged

• Cat.No.: SNPH-27725TH
• Product Overview: Recombinant fragment corresponding to amino acids 1-424 of human SNPH with His tag; 444 amino acids, 48.2 KDa.

Specification

• Description: Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Brain specific. Found in synapses.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAMSLPGSRR TSAGSRRRTS PPVSVRDAYG TSSLSSSSNS GSYKGSDSSP TPRRSMKYTL CSDNHGIKPP TPEQYLTPLQ QKEVCIRHLK ARLKDTQDRL QDRDTEIDDL KTQLSRMQED WIEEECHRVE AQLALKEARK EIKQLKQVID TVKNNLIDKD KGLQKYFVDI NIQNKKLETL LHSMEVAQNG MAKEDGTGES AGGSPARSLT RSSTYTKLSD PAVCGDRQPG DPSSGSAEDG ADSGFAAADD TLSRTDALEA SSLLSSGVDC GTEETSLHSS FGLGPRFPAS NTYEKLLCGM EAGVQASCMQ ERAIQTDFVQ YQPDLDTILE KVTQAQVCGT DPESGDRCPE LDAHPSGPRD PNSAVVVTVG DELEAPEPIT RGPTPQRPGA NPNPGQSVSV VCPMEEEEEA AVAEKEPKSY WSRH

Gene Information

• Gene Name: SNPH syntaphilin [ Homo sapiens ]
• Official Symbol: SNPH
• Synonyms: SNPH; syntaphilin; bA314N13.5
• Gene ID: 9751
• mRNA Refseq: NM_014723
• Protein Refseq: NP_055538
• MIM: 604942
• Uniprot ID: O15079
• Chromosome Location: 20p13
• Function: syntaxin-1 binding