Recombinant Human Poly (ADP-ribose) Polymerase 1, GST-tagged

• Cat.No.: PARP1-430H
• Product Overview: Recombinant Human PARP1, full length with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW = 140kDa.

Specification

• Cat. No.: PARP1-430H
• Description: Poly [ADP-ribose] polymerase 1 is an enzyme that in humans is encoded by the PARP1 gene.
• Source: Sf9 cell.
• Purity: >80%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: PARP1 poly (ADP-ribose) polymerase 1 [ Homo sapiens ]
• Synonyms: PARP1; poly (ADP-ribose) polymerase 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase NAD(+); poly (ADP-ribose) polymerase family, member 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; PARP; PPOL; ADPRT; ADPRT1; PARP-1; pADPRT-1; EC 2.4.2.30
• Gene ID: 142
• mRNA Refseq: NM_001618
• Protein Refseq: NP_001609
• MIM: 173870
• UniProt ID: P09874
• Chromosome Location: 1q41-q42
• Pathway: Base excision repair
• Function: DNA binding; NAD or NADH binding; NAD+ ADP-ribosyltransferase activity; identical protein binding; protein N-terminus binding; transcription factor binding; transferase activity, transferring glycosyl groups; zinc ion binding