"SOX9" Related Products


Recombinant Human SOX9

Cat.No. : SOX9-30694TH
Product Overview : Recombinant fragment of Human SOX9 fused to a proprietary tag, predicted MWt 43kDa inclusive of tag.
Description : The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Protein length : 150 amino acids
Molecular Weight : 43.000kDa inclusive of tags
Source : E. coli
Form : Liquid
Storage buffer : pH: 7.50Constituents:0.03% EDTA, 20% Glycerol, 0.91% Tris acetate
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Contains 1 HMG box DNA-binding domain.
Gene Name : SOX9 SRY (sex determining region Y)-box 9 [ Homo sapiens ]
Official Symbol : SOX9
Synonyms : SOX9; SRY (sex determining region Y)-box 9; campomelic dysplasia, autosomal sex reversal , CMD1, CMPD1; transcription factor SOX-9; SRA1;
Gene ID : 6662
mRNA Refseq : NM_000346
Protein Refseq : NP_000337
MIM : 608160
Uniprot ID : P48436
Chromosome Location : 17q23
Pathway : Endochondral Ossification, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem;
Function : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; beta-catenin binding; chromatin binding; core promoter sequence-specific DNA binding; enhancer bi;

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