Native Human SPARC

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Native Human SPARC

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Cat.No. : SPARC-30653TH
Product Overview : Full length Human SPARC isolated from thrombin activated platelets; amino acids 18-303 , Predicted MWt 32.7kDa.
Description : Secreted protein acidic and rich in cysteine/osteonectin/BM40, or SPARC, is a matrix-associated protein that elicits changes in cell shape, inhibits cell-cycle progression, and influences the synthesis of extracellular matrix (ECM) (Bradshaw et al.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20mM Tris, 150mM Sodium chloride, pH 7.4
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the SPARC family.Contains 1 EF-hand domain.Contains 1 follistatin-like domain.Contains 1 Kazal-like domain.
Gene Name : SPARC secreted protein, acidic, cysteine-rich (osteonectin) [ Homo sapiens ]
Official Symbol : SPARC
Synonyms : SPARC; secreted protein, acidic, cysteine-rich (osteonectin); ON; cysteine rich protein; osteonectin;
Gene ID : 6678
mRNA Refseq : NM_003118
Protein Refseq : NP_003109
MIM : 182120
Uniprot ID : P09486
Chromosome Location : 5q31-q33
Pathway : Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem; Senescence and Autophagy, organism-specific biosystem;
Function : calcium ion binding; collagen binding; extracellular matrix binding; protein binding;

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