Recombinant Mouse Phosphodiesterase 10A, GST-tagged

• Cat.No.: Pde10a-438M
• Product Overview: Recombinant mouse Pde10a, full length with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW = 114.5kDa.

Specification

• Cat. No.: Pde10a-438M
• Description: Phosphodiesterase 10A is an enzyme that in humans is encoded by the PDE10A gene.
• Source: Sf9 cell.
• Purity: >80%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: Pde10a phosphodiesterase 10A [ Mus musculus ]
• Synonyms: Pde10a; phosphodiesterase 10A; OTTMUSP00000024055; PDE10A2 brain-specific isoform; dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase; EC 3.1.4.17; EC 3.1.4.35
• Gene ID: 23984
• mRNA Refseq: NM_011866
• Protein Refseq: NP_035996
• UniProt ID: Q8CA95
• Chromosome Location: 17 A1
• Pathway: Progesterone-mediated oocyte maturation; Purine metabolism
• Function: 3",5"-cyclic-GMP phosphodiesterase activity; 3",5"-cyclic-nucleotide phosphodiesterase activity; cGMP binding; cAMP binding; catalytic activity; magnesium ion binding; nucleotide binding; zinc ion binding