Recombinant Human TDO2

• Cat.No.: TDO2-31212TH
• Product Overview: Recombinant full length Human TDO2 protein, 46.7kDa .

Specification

• Description: Tryptophan 2,3-dioxygenase (EC 1.13.11.11) plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism.
• Source: E. coli
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the tryptophan 2,3-dioxygenase family.

Gene Information

• Gene Name: TDO2 tryptophan 2,3-dioxygenase [ Homo sapiens ]
• Official Symbol: TDO2
• Synonyms: TDO2; tryptophan 2,3-dioxygenase; TDO; TPH2
• Gene ID: 6999
• mRNA Refseq: NM_005651
• Protein Refseq: NP_005642
• MIM: 191070
• Uniprot ID: P48775
• Chromosome Location: 4q31-q32
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Monoamine Transport, organism-specific biosystem; NAD biosynthesis II (from tryptophan), conserved biosystem
• Function: amino acid binding; heme binding; metal ion binding; oxidoreductase activity; oxygen binding