Recombinant Human TES TES-31216TH

Recombinant Human TES

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Recombinant Human TES

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Cat.No. : TES-31216TH
Product Overview : Recombinant full lengthhuman Testin protein, 48 kDa.
Description : Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Gene Name : TES testis derived transcript (3 LIM domains) [ Homo sapiens ]
Official Symbol : TES
Synonyms : TES; testis derived transcript (3 LIM domains); testin; DKFZP586B2022; TESS 2; TESTIN;
Gene ID : 26136
mRNA Refseq : NM_015641
Protein Refseq : NP_056456
MIM : 606085
Uniprot ID : Q9UGI8
Chromosome Location : 7q31.2
Function : metal ion binding; zinc ion binding;

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