Recombinant Human TES

• Cat.No.: TES-31216TH
• Product Overview: Recombinant full lengthhuman Testin protein, 48 kDa.

Specification

• Description: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: TES testis derived transcript (3 LIM domains) [ Homo sapiens ]
• Official Symbol: TES
• Synonyms: TES; testis derived transcript (3 LIM domains); testin; DKFZP586B2022; TESS 2; TESTIN
• Gene ID: 26136
• mRNA Refseq: NM_015641
• Protein Refseq: NP_056456
• MIM: 606085
• Uniprot ID: Q9UGI8
• Chromosome Location: 7q31.2
• Function: metal ion binding; zinc ion binding