Recombinant Human TFAM, His-tagged
Cat.No. : | TFAM-30255TH |
Product Overview : | Recombinant full length Human mtTFA with N terminal His tag; 225 amino acids with tag, MWt 26.6 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells. |
Protein length : | 204 amino acids |
Conjugation : | HIS |
Molecular Weight : | 26.600kDa inclusive of tags |
Source : | E. coli |
Form : | Liquid |
Purity : | by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMSSVL ASCPKKPVSSYLRFSKEQLPIFKAQ NPDAKTTELIRRIAQRWRELPDSKK KIYQDAYRAEWQVYKEEISRFKEQL TPSQIMSLEKEIMDKHLKRKAMTKK KELTLLGKPKRPRSAYNVYVAERFQ EAKGDSPQEKLKTVKENWKNLSDSE KELYIQHAKEDETRYHNEMKSWEEQ MIEVGRKDLLRRTIKKQRKYGAEEC |
Sequence Similarities : | Contains 2 HMG box DNA-binding domains. |
Gene Name : | TFAM transcription factor A, mitochondrial [ Homo sapiens ] |
Official Symbol : | TFAM |
Synonyms : | TFAM; transcription factor A, mitochondrial; TCF6, TCF6L2; |
Gene ID : | 7019 |
mRNA Refseq : | NM_003201 |
Protein Refseq : | NP_003192 |
MIM : | 600438 |
Uniprot ID : | Q00059 |
Chromosome Location : | 10q21 |
Pathway : | Energy Metabolism, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Mitochondrial Gene Expression, organism-specific biosystem; Mitochondrial transcription initiation, organism-specific biosystem; |
Function : | DNA binding; chromatin binding; mitochondrial light strand promoter sense binding; protein binding; sequence-specific DNA binding transcription factor activity; |
Products Types
◆ Recombinant Protein | ||
Tfam-655M | Recombinant Mouse Tfam Protein, His/GST-tagged | +Inquiry |
Tfam-656R | Recombinant Rat Tfam Protein, His/GST-tagged | +Inquiry |
TFAM-5683R | Recombinant Rat TFAM Protein, His (Fc)-Avi-tagged | +Inquiry |
TFAM-654H | Recombinant Human TFAM Protein, His/GST-tagged | +Inquiry |
TFAM-9148M | Recombinant Mouse TFAM Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TFAM-1765HCL | Recombinant Human TFAM cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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