Recombinant Human THPO
| Cat.No. : | THPO-29520TH |
| Product Overview : | Recombinant full length protein (Human) |
- Specification
- Gene Information
- Related Products
| Description : | Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene. |
| Protein length : | 174 amino acids |
| Source : | E. coli |
| Form : | Lyophilised |
| Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Sequences of amino acids : | Recombinant human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein.SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNEL |
| Sequence Similarities : | Belongs to the EPO/TPO family. |
| Gene Name : | THPO thrombopoietin [ Homo sapiens ] |
| Official Symbol : | THPO |
| Synonyms : | THPO; thrombopoietin; MGDF; c mpl ligand; megakaryocyte colony stimulating factor; megakaryocyte growth and development factor; megakaryocyte stimulating factor; MPL ligand; MPLLG; myeloproliferative leukemia virus oncogene ligand; thrombopoietin nirs var |
| Gene ID : | 7066 |
| mRNA Refseq : | NM_000460 |
| Protein Refseq : | NP_000451 |
| MIM : | 600044 |
| Uniprot ID : | P40225 |
| Chromosome Location : | 3q27 |
| Pathway : | Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Hemostasis, organism-specific biosystem; Platelet Aggregation (Plug Formation), organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; |
| Function : | cytokine activity; growth factor activity; hormone activity; |
Products Types
| ◆ Recombinant Protein | ||
| THPO-289H | Recombinant Human THPO Protein (Ser22-Leu195), N-His tagged, Animal-free, Carrier-free | +Inquiry |
| Thpo-111M | Recombinant Mouse Thpo Protein, His (Fc)-Avi-tagged | +Inquiry |
| THPO-01H | Active Recombinant Human THPO Protein, His-tagged | +Inquiry |
| THPO-4327B | Recombinant Bovine THPO Protein | +Inquiry |
| THPO-2752H | Recombinant Human THPO protein(22-353 aa), N-MBP & C-His-tagged | +Inquiry |
| ◆ Lysates | ||
| THPO-2831MCL | Recombinant Mouse THPO cell lysate | +Inquiry |
| THPO-2832HCL | Recombinant Human THPO cell lysate | +Inquiry |
| THPO-2273CCL | Recombinant Cynomolgus THPO cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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