Recombinant Human TIAM2, His-tagged
Cat.No. : | TIAM2-30624TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 1134-1701 of Human TIAM2 with N terminal His tag, 568 amino acids, 80kDa, |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Expressed in the occipital, frontal and temporal lobes, cerebellum, putamen and testis. |
Form : | Lyophilised:Reconstitution with 153 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | FLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNT LETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKV QKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQR VLKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASH INEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMH STVSWLNPFLSLGKARKDLELTVFVFKRAVILVYKENC KLKKKLPSNSRPAHNSTDLDPFKFRWLIPISALQVRLGNP AGTENNSIWELIHTKSEIEGRPETIFQLCCSDSESKTN IVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPV SAKLASSRSLKVLKNSSSNEWTGETGKGTLLDSDEGSL SSGTQSSGCPTAEGRQDSKSTSPGKYPHPGLADFADNL IKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDP DVHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKA NSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVLEREFS VQSLTSVVSEECFYETESHGKS |
Sequence Similarities : | Belongs to the TIAM family.Contains 1 DH (DBL-homology) domain.Contains 1 PDZ (DHR) domain.Contains 2 PH domains.Contains 1 RBD (Ras-binding) domain. |
Gene Name : | TIAM2 T-cell lymphoma invasion and metastasis 2 [ Homo sapiens ] |
Official Symbol : | TIAM2 |
Synonyms : | TIAM2; T-cell lymphoma invasion and metastasis 2; T-lymphoma invasion and metastasis-inducing protein 2; STEF; |
Gene ID : | 26230 |
mRNA Refseq : | NM_001010927 |
Protein Refseq : | NP_001010927 |
MIM : | 604709 |
Uniprot ID : | Q8IVF5 |
Chromosome Location : | 6q25 |
Pathway : | Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; |
Function : | Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; receptor signaling protein activity; |
Products Types
◆ Recombinant Protein | ||
Tiam2-6425M | Recombinant Mouse Tiam2 Protein, Myc/DDK-tagged | +Inquiry |
TIAM2-1048H | Recombinant Human TIAM2 Protein, MYC/DDK-tagged | +Inquiry |
TIAM2-9206M | Recombinant Mouse TIAM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TIAM2-16771M | Recombinant Mouse TIAM2 Protein | +Inquiry |
TIAM2-4637C | Recombinant Chicken TIAM2 | +Inquiry |
◆ Lysates | ||
TIAM2-1780HCL | Recombinant Human TIAM2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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