Recombinant Rat Selectin E

• Cat.No.: Sele-1791R

Specification

• Cat. No.: Sele-1791R
• Description: E-selectin, also known as CD62E is an inducible leukocyte adhesion glycoprotein specifically expressed by endothelial cells. E-selectin helps initiate recruitment of circulating leukocytes to cutaneous, bone and inflamed tissues. E-selectin is found in inflammatory skin lesions in psoriasis, contact dermatitis, and delayed- type hypersensitivity, in arthritic joints, and in heart and renal allografts undergoing rejection. E-selectin-targeting antibody drug conjugate has potential as a prostate cancer therapy.
• Molecular Weight: The predicted molecular weight of Recombinant Rat E-Selectin is Mr 78 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110-120 kDa.
• Source: Mammalian cells
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Sele selectin E [ Rattus norvegicus ]
• Synonyms: Sele; selectin E; endothelial cell; selectin
• Gene ID: 25544
• mRNA Refseq: NM_138879
• Protein Refseq: NP_620234
• UniProt ID: P98105
• Chromosome Location: 13q22
• Pathway: Cell adhesion molecules (CAMs)
• Function: molecular_function; oligosaccharide binding; phospholipase binding; protein binding; sialic acid binding; sugar binding; transmembrane receptor activity