"Sigirr" Related Products

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Recombinant Mouse Sigirr

Cat. No.: Sigirr-501M
Description: Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family. It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling. It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium.
Source: NSO Cells.
Molecular Weight: The predicted molecular weight of Recombinant Mouse SIGIRR is Mr 39 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 63 kDa.
State Of Matter: Lyophilized.
Purity: >95% by SDS Page and analyzed by silver stain.
Endotoxin: <0.1 ng per 1 µg as determined by the LAL method.
Storage And Stability: The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name: Sigirr single immunoglobulin and toll-interleukin 1 receptor (TIR) domain [ Mus musculus ]
Synonyms: Sigirr; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; TIR8; AI256711; MGC102426; single Ig IL-1 receptor related protein; single Ig IL-1R-related protein
Gene ID: 24058
mRNA Refseq: NM_023059
Protein Refseq: NP_075546
UniProt ID: Q9JLZ8
Chromosome Location: 7 F5
Function: receptor activity; transmembrane receptor activity

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