Recombinant Human TNKS

• Cat.No.: TNKS-31498TH
• Product Overview: Recombinant fragment of Human Tankyrase with a proprietary tag: predicted molecular weight 37.51 kDa.

Specification

• Description: Tankyrase-1 is an enzyme that in humans is encoded by the TNKS gene.
• Protein length: 108 amino acids
• Molecular Weight: 37.510kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Ubiquitous; highest levels in testis.
• Biological activity: This product is useful for Antibody Production and Protein Array
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: TERKEGEVAGLDMNISQFLKSLGLE HLRDIFETEQITLDVLADMGHEELK EIGINAYGHRHKLIKGVERLLGGQQ GTNPYLTFHCVNQGTILLDLAPEDK EYQSVEEE
• Sequence Similarities: Contains 15 ANK repeats.Contains 1 PARP catalytic domain.Contains 1 SAM (sterile alpha motif) domain.

Gene Information

• Gene Name: TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase [ Homo sapiens ]
• Official Symbol: TNKS
• Synonyms: TNKS; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; tankyrase-1; PARP 5a; PARP5A; pART5; TIN1; TINF1; TNKS1
• Gene ID: 8658
• mRNA Refseq: NM_003747
• Protein Refseq: NP_003738
• MIM: 603303
• Uniprot ID: O95271
• Chromosome Location: 8p23.1
• Pathway: Regulation of Telomerase, organism-specific biosystem
• Function: NAD+ ADP-ribosyltransferase activity; protein binding; transferase activity, transferring glycosyl groups; zinc ion binding