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Recombinant Human TOLLIP, His-tagged

Cat.No. : TOLLIP-29826TH
Product Overview : Recombinant full-length Human Tollip with a N terminal His tag; 294 amino acids, predicted molecular weight 32.4 kDa
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  • Gene Information
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Description : This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase.
Protein length : 294 amino acids
Conjugation : HIS
Molecular Weight : 32.400kDa inclusive of tags
Source : E. coli
Form : Liquid
Purity : by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 40% Glycerol, 0.2M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLVPRGSHMATTV STQRGPVYIGELPQDFLRITPTQQQ RQVQLDAQAAQQLQYGGAVGTVGRL NITVVQAKLAKNYGMTRMDPYCRLR LGYAVYETPTAHNGAKNPRWNKVIH CTVPPGVDSFYLEIFDERAFSMDDR IAWTHITIPESLRQGKVEDKWYSLS GRQGDDKEGMINLVMSYALLPAAMV MPPQPVVLMPTVYQQGVGYVPITGM PAVCSPGMVPVALPPAAVNAQPRCS EEDLKAIQDMFPNMDQEVIRSVLEA QRGNKDAAINSLLQMGEEP
Sequence Similarities : Belongs to the tollip family.Contains 1 C2 domain.Contains 1 CUE domain.
Gene Name : TOLLIP toll interacting protein [ Homo sapiens ]
Official Symbol : TOLLIP
Synonyms : TOLLIP; toll interacting protein; toll-interacting protein; IL 1RAcPIP;
Gene ID : 54472
mRNA Refseq : NM_019009
Protein Refseq : NP_061882
MIM : 606277
Uniprot ID : Q9H0E2
Chromosome Location : 11p
Pathway : Cytokine Signaling in Immune system, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem; Signaling by Interleukins, organism-specific biosystem;
Function : Toll-like receptor binding; kinase binding; protein binding; signal transducer activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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