Recombinant Human TUFM, His-tagged

• Cat.No.: TUFM-31633TH
• Product Overview: Recombinant fragment, corresponding to amino acids 211-452 of Human TUFM with an N terminal His tag. Predicted MWt: 28 kDa,

Specification

• Description: This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 69 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: EETPVIVGSALCALEGRDPELGLKSVQKLLDAVDTYIPVP ARDLEKPFLLPVEAVYSVPGRGTVVTGTLERGILKKGD ECELLGHSKNIRTVVTGIEMFHKSLERAEAGDNLGALV RGLKREDLRRGLVMVKPGSIKPHQKVEAQVYILSKEEGGR HKPFVSHFMPVMFSLTWDMACRIILPPEKELAMPGEDL KFNLILRQPMILEKGQRFTLRDGNRTIGTGLVTNTLAM TEEEKNIKWG

Gene Information

• Gene Name: TUFM Tu translation elongation factor, mitochondrial [ Homo sapiens ]
• Official Symbol: TUFM
• Synonyms: TUFM; Tu translation elongation factor, mitochondrial; elongation factor Tu, mitochondrial; EF TuMT; EFTu; EFTU
• Gene ID: 7284
• mRNA Refseq: NM_003321
• Protein Refseq: NP_003312
• MIM: 602389
• Uniprot ID: P49411
• Chromosome Location: 16p11.2
• Function: GTP binding; GTPase activity; nucleotide binding; translation elongation factor activity