|Product Overview :||Recombinant Mouse Tgfbr1((Ala21-Glu121) & (Thr22-Glu121)) fused with an C-terminal Fc tag was expressed in Insect cells.|
|Source :||Insect cells|
|Predicted N Terminal :||Ala21 & Thr22|
|Form :||Lyophilized from a 0.2 μm filtered solution in PBS.|
|Bio-activity :||Measured by its binding ability in a functional ELISA. When Recombinant Rat Endoglin/CD105 Fc Chimera or Recombinant Mouse Endoglin/CD105 Fc Chimera is immobilized at 2 μg/mL (100 μL/well), the concentration of Recombinant Mouse TGF-beta RI/ALK-5 Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.25-1.25 μg/mL.|
|Molecular Mass :||Predicted Molecular Mass: 37.5 (monomer) kDa;
SDS-PAGE: 40-50 kDa, reducing conditions.
|Endotoxin :||<0.10 EU per 1 μg of the protein by the LAL method.|
|Purity :||>90%, by SDS-PAGE under reducing conditions and visualized by silver stain|
|Storage :||Avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
|Reconstitution :||Reconstitute at 500 μg/mL in sterile PBS.|
|Gene Name :||Tgfbr1 transforming growth factor, beta receptor I [ Mus musculus ]|
|Official Symbol :||Tgfbr1|
|Synonyms :||TGFBR1; transforming growth factor, beta receptor I; TGF-beta receptor type-1; ESK2; TGFR-1; TGF-beta receptor type I; transforming growth factor-beta receptor type I; ALK5; Alk-5; TbetaRI; AU017191; TbetaR-I;|
|Gene ID :||21812|
|mRNA Refseq :||NM_009370|
|Protein Refseq :||NP_033396|
|UniProt ID :||Q64729|