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Native Human VTN

Cat.No.: VTN-31735TH
Product Overview: Full length native multimeric Vitronectin from Human plasma. Predicted MWt: 42 kDa ;
Description: The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Tissue specificity: Plasma.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 0.1M Sodium chloride, 0.05M Sodium phosphate, pH 7.4
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Contains 4 hemopexin-like domains.Contains 1 SMB (somatomedin-B) domain.
Gene Name: VTN vitronectin [ Homo sapiens ]
Official Symbol: VTN
Synonyms: VTN; vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S protein); complement S protein; serum spreading factor; somatomedin B; VN;
Gene ID: 7448
mRNA Refseq: NM_000638
Protein Refseq: NP_000629
MIM: 193190
Uniprot ID: P04004
Chromosome Location: 17q11.2
Pathway: ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; FOXA1 transcription factor network, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem;
Function: extracellular matrix binding; heparin binding; integrin binding; polysaccharide binding; scavenger receptor activity;

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