Native Human VTN

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Cat.No. :	VTN-31737TH
Product Overview :	Full length native multimeric Vitronectin from Human plasma. Predicted MWt: 75,000 , 420,000 ;
Description :	The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Tissue specificity :	Plasma.
Form :	Liquid
Purity :	>95% by SDS-PAGE
Storage buffer :	Preservative: NoneConstituents: 0.1M Sodium chloride, 0.05M Sodium phosphate, pH 7.4
Storage :	Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities :	Contains 4 hemopexin-like domains.Contains 1 SMB (somatomedin-B) domain.

Gene Name :	VTN vitronectin [ Homo sapiens ]
Official Symbol :	VTN
Synonyms :	VTN; vitronectin; vitronectin (serum spreading factor, somatomedin B, complement S protein); complement S protein; serum spreading factor; somatomedin B; VN;
Gene ID :	7448
mRNA Refseq :	NM_000638
Protein Refseq :	NP_000629
MIM :	193190
Uniprot ID :	P04004
Chromosome Location :	17q11.2
Pathway :	ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; FOXA1 transcription factor network, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem;
Function :	extracellular matrix binding; heparin binding; integrin binding; polysaccharide binding; scavenger receptor activity;