Recombinant Human XCL1

• Cat.No.: XCL1-27983TH
• Product Overview: Recombinant fragment, corresponding to amino acids 23-114 of Human Lymphotactin, 92 amino acids, 10kDa.

Specification

• Description: This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.
• Source: E. coli
• Tissue specificity: Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.
• Biological activity: Biological Activity:The Biological activity is calculated by its ability to chemoattract human T cells at 10.0-100.0 ng/ml.
• Form: Lyophilised:Reconstitute in sterile 18MO-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.Upon reconstitution XCL1-27983TH should be stored at 4°C between 2-7 days and for future use below -18°C. For long term st
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: ddH20
• Storage: Store at -20°C or lower.Aliquot to avoid repeated freezing and thawing.
• Sequences of amino acids: The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Ser-Glu-Val-Ser.
• Sequence Similarities: Belongs to the intercrine gamma family.

Gene Information

• Gene Name: XCL1 chemokine (C motif) ligand 1 [ Homo sapiens ]
• Official Symbol: XCL1
• Synonyms: XCL1; chemokine (C motif) ligand 1; LTN, SCYC1, small inducible cytokine subfamily C, member 1 (lymphotactin); lymphotactin; ATAC; LPTN; SCM 1; SCM 1a
• Gene ID: 6375
• mRNA Refseq: NM_002995
• Protein Refseq: NP_002986
• MIM: 600250
• Uniprot ID: P47992
• Chromosome Location: 1q24.2
• Pathway: Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem
• Function: chemokine activity; chemokine receptor binding; chemokine receptor binding; protein homodimerization activity