Recombinant Human UBA1, GST-tagged

• Cat.No.: UBA1-476H
• Product Overview: Recombinant Human UBA1, amino acids 2-end with N-terminal FLAG tag expressed inSf9expression system. MW = 118kDa.

Specification

• Cat. No.: UBA1-476H
• Description: Ubiquitin-like modifier activating enzyme 1, also known as UBA1, is an enzyme which in humans is encoded by the UBA1 gene. In non-primates, the gene UBE1, rather than the SRY gene, is commonly used for sexual determination.
• Source: Sf9.
• Purity: >65%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: UBA1 ubiquitin-like modifier activating enzyme 1 [ Homo sapiens ]
• Synonyms: UBA1; ubiquitin-like modifier activating enzyme 1; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; SMAX2; UBA1A; UBE1X; MGC4781; UBA1, ubiquitin-activating enzyme E1 homolog A; A1S9T and BN75 temperature sensitivity complementing; ubiquitin-activating enzyme E1; EC 6.3.2.19
• Gene ID: 7317
• mRNA Refseq: NM_003334
• Protein Refseq: NP_003325
• MIM: 314370
• UniProt ID: P22314
• Chromosome Location: Xp11.23
• Pathway: Parkinson"s disease; Ubiquitin mediated proteolysis
• Function: ATP binding; ligase activity; nucleotide binding; small protein activating enzyme activity; protein binding