"WWP1" Related Products

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Recombinant Human WWP1, GST-tagged

Cat. No. : WWP1-477H
Product Overview : Recombinant Human WWP1, amino acids 2-end with N-terminal FLAG tag expressed inSf9expression system. MW = 106kDa.
Description : NEDD4-like E3 ubiquitin-protein ligase WWP1 is an enzyme that in humans is encoded by the WWP1 gene. WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain.
Source : Sf9.
Purity : >15%.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
Stability : >6 months at –80°C.
Gene Name : WWP1 WW domain containing E3 ubiquitin protein ligase 1 [ Homo sapiens ]
Synonyms : WWP1; WW domain containing E3 ubiquitin protein ligase 1; AIP5; Tiul1; hSDRP1; DKFZp434D2111; WW domain containing E3 ubiquitin protein ligase 1; atrophin-1 interacting protein 5; TGIF-interacting ubiquitin ligase 1; Nedd-4-like ubiquitin-protein ligase
Gene ID : 11059
mRNA Refseq : NM_007013
Protein Refseq : NP_008944
MIM : 602307
UniProt ID : Q9H0M0
Chromosome Location : 8q21
Pathway : Endocytosis; Ubiquitin mediated proteolysis
Function : acid-amino acid ligase activity; ligase activity; ubiquitin-protein ligase activity; protein binding

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