Recombinant Human Phenylethanolamine N-methyltransferase
Cat.No. : | PNMT-481H |
Product Overview : | Recombinant human PNMT protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 30.8 Da (282aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | PNMT-481H |
Description : | PNMT, also known as phenylethanolamine N-methyltransferase, is an enzyme found in the adrenal medulla that catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. |
Source : | E.coli. |
Amino Acid Sequence : | MSGADRSPNA GAAPDSAPGQ AAVASAYQRF EPRAYLRNNY APPRGDLCNP NGVGPWKLRC LAQTFATGEV SGRTLIDIGS GPTVYQLLSA CSHFEDITMT DFLEVNRQEL GRWLQEEPGA FNWSMYSQHA CLIEGKGECW QDKERQLRAR VKRVLPIDVH QPQPLGAGSP APLPADALVS AFCLEAVSPD LASFQRALDH ITTLLRPGGH LLLIGALEES WYLAGEARLT VVPVSEEEVR EALVRSGYKV RDLRTYIMPA HLQTGVDDVK GVFFAWAQKV GL |
Form : | Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol. |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1.0 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Publication : |
Noncompetitive Inhibition of Indolethylamine N-Methyltransferase by N, N Dimethyltryptamine (DMT) and N, N-Dimethylaminopropyltryptamine (2014)
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Gene Name : | PNMT phenylethanolamine N-methyltransferase [ Homo sapiens ] |
Synonyms : | PNMT; phenylethanolamine N-methyltransferase; PENT; PNMTase; MGC34570; phenylethanolamine N-methyltransferase; phenylethanolamine N-methylase; noradrenaline N-methyltransferase; EC 2.1.1.28; OTTHUMP00000164271 |
Gene ID : | 5409 |
mRNA Refseq : | NM_002686 |
Protein Refseq : | NP_002677 |
MIM : | 171190 |
UniProt ID : | P11086 |
Chromosome Location : | 17q21-q22 |
Pathway : | Metabolic pathways; Tyrosine metabolism |
Function : | methyltransferase activity; phenylethanolamine N-methyltransferase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
PNMT-1722H | Recombinant Human PNMT Protein, His (Fc)-Avi-tagged | +Inquiry |
PNMT-4209R | Recombinant Rat PNMT Protein, His (Fc)-Avi-tagged | +Inquiry |
PNMT-6884M | Recombinant Mouse PNMT Protein, His (Fc)-Avi-tagged | +Inquiry |
PNMT-01H | Active Recombinant Human PNMT Protein, His-tagged | +Inquiry |
Pnmt-4969M | Recombinant Mouse Pnmt Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
PNMT-3075HCL | Recombinant Human PNMT 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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